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4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated

Catalog No. TMPJ-00140
Synonyms: CD137, CDw137, 4-1BB ligand receptor, ILA, T-cell antigen ILA, TNFRSF9, T-cell antigen 4-1BB homolog

Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation. 4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 25-38 kDa and the accession number is A9YYE7.

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4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
Pack Size Availability Price/USD Quantity
20 μg 5 days $ 355.00
100 μg 5 days $ 963.00
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Biological Description
Technical Params
Product Properties
Description Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation. 4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 25-38 kDa and the accession number is A9YYE7.
Species Cynomolgus
Expression System HEK293 Cells
Tag C-6xHis-Avi
Accession Number A9YYE7
Synonyms CD137, CDw137, 4-1BB ligand receptor, ILA, T-cell antigen ILA, TNFRSF9, T-cell antigen 4-1BB homolog
Amino Acid Leu24-Gln186
Construction Leu24-Gln186
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 25-38 kDa (reducing condition)
Endotoxin < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation.

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Keywords

4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated TNFRSF-9 CD 137 CD137 CDw137 4-1BB ligand receptor ILA T-cell antigen ILA TNFRSF 9 CD-137 TNFRSF9 T-cell antigen 4-1BB homolog recombinant recombinant-proteins proteins protein

 

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