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Synonyms: IRE1P, IRE1a, IRE1, hIRE1p, endoplasmic reticulum to nucleus signaling 1

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $63 | - | In Stock | |
| 10 μg | $100 | - | In Stock | |
| 20 μg | $163 | 7-10 days | 7-10 days | |
| 50 μg | $320 | 7-10 days | 7-10 days | |
| 100 μg | $547 | 7-10 days | 7-10 days | |
| 200 μg | $935 | 7-10 days | 7-10 days | |
| 500 μg | $1,890 | 7-10 days | 7-10 days |
| Bioactivity | Measured by its nuclease activity to cleave Xbp1 single stem-loop mini-substrate. |
| Description | IRE1 Protein, Human, Recombinant (aa 465-977) is expressed in Baculovirus insect cells. The predicted molecular weight is 58.3 kDa and the accession number is O75460-1. |
| Species | Human |
| Expression System | Baculovirus Insect Cells |
| Tag | Tag Free |
| Accession Number | O75460-1 |
| Construction | A DNA sequence encoding the human ERN1 (O75460-1) (Pro 465-Leu 977) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus. Predicted N terminal: Gly |
| Protein Purity | > 80 % as determined by SDS-PAGE ![]() |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as sterile 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 7.4. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Stability & Storage | It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | IRE1P, IRE1a, IRE1, hIRE1p, endoplasmic reticulum to nucleus signaling 1 |
| Research Background |
| Molecular Weight | 58.3 kDa (predicted); 65 kDa (reducing condition, due to glycosylation) |
| Storage | Store at low temperature Store at -80°C |
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