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Angiotensin II (3-8), human TFA

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Catalog No. T10323

Angiotensin II (3-8), human (TFA), is an angiotensin AT1 receptor agonist with reduced activity.

Angiotensin II (3-8), human TFA
Other Forms of Angiotensin II (3-8), human TFA:
Angiotensin II (1-4), human TFATP1661
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Angiotensin II (3-8), human TFA

😃Good
Catalog No. T10323
Angiotensin II (3-8), human (TFA), is an angiotensin AT1 receptor agonist with reduced activity.
Pack SizePriceAvailabilityQuantity
5 mg$75Backorder
10 mg$125Backorder
25 mg$257Backorder
50 mgInquiryBackorder
100 mgInquiryBackorder
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Product Introduction

Bioactivity
Description
Angiotensin II (3-8), human (TFA), is an angiotensin AT1 receptor agonist with reduced activity.
In vivo
In anesthetized rats, Human Angiotensin II (3-8) induces endothelium-dependent renal cortical vasodilation. At doses up to 125 pmol/kg, it exerts no cardiovascular effects. However, at doses of 1.25 and 12.5 nmol/kg, it causes dose-dependent elevations in mean arterial blood pressure along with decreases in renal and mesenteric flows and vascular conductances.
Chemical Properties
Molecular Weight888.93
FormulaC42H55F3N8O10
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 50 mg/mL (56.25 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.1249 mL5.6247 mL11.2495 mL56.2474 mL
5 mM0.2250 mL1.1249 mL2.2499 mL11.2495 mL
10 mM0.1125 mL0.5625 mL1.1249 mL5.6247 mL
20 mM0.0562 mL0.2812 mL0.5625 mL2.8124 mL
50 mM0.0225 mL0.1125 mL0.2250 mL1.1249 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

Angiotensin II , human TFAAngiotensin II (38), human TFAAngiotensin II (3 8), human TFAAngiotensin AT1 receptor
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