keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
YAP-TEAD-IN-1 is a competitive inhibitor of YAP–TEAD interaction (IC50: 25 nM). It shows a higher binding affinity to TEAD1 (Kd: 15 nM) than YAP (50-171) (Kd: 40 nM).
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Description | YAP-TEAD-IN-1 is a competitive inhibitor of YAP–TEAD interaction (IC50: 25 nM). It shows a higher binding affinity to TEAD1 (Kd: 15 nM) than YAP (50-171) (Kd: 40 nM). |
Targets&IC50 | YAP-TEAD:25 nM |
In vitro | In a GST pull-down assay, YAP-TEAD-IN-1 (2 μM) is against endogenous YAP binding to GST-TEAD (1209-426), the Kd of His-YAP1209-426 is determined to be 40 nM. |
Molecular Weight | 2019.89 |
Formula | C93H144ClN23O21S2 |
CAS No. | 1659305-78-8 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
YAP-TEAD-IN-1 1659305-78-8 Others YAPTEADIN1 YAP TEAD IN 1 inhibitor inhibit