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Urotensin II (114-124), human acetate

Urotensin II (114-124), human acetate
Urotensin II (114-124), human acetate is an 11-amino acid residue peptide, is a potent vasoconstrictor and agonist for the orphan receptor GPR14.
Catalog No. TP1737L
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Purity:100%
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Urotensin II (114-124), human acetate

Catalog No. TP1737L
Urotensin II (114-124), human acetate is an 11-amino acid residue peptide, is a potent vasoconstrictor and agonist for the orphan receptor GPR14.
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Pack SizePriceAvailabilityQuantity
1 mg$196In Stock
5 mg$487In Stock
10 mg$696In Stock
25 mg$1,090In Stock
50 mg$1,490In Stock
100 mg$1,980In Stock
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Product Introduction

Bioactivity
Description
Urotensin II (114-124), human acetate is an 11-amino acid residue peptide, is a potent vasoconstrictor and agonist for the orphan receptor GPR14.
In vitro
Human Urotensin II (U-II) binds to recombinant human GPR14 with high affinity, and the binding is functionally coupled to calcium mobilization. Human Urotensin II induces concentration-dependent increases in intracellular calcium in a HEK-293 cell line expressing human GPR14 (EC50=0:62±0.17 nM, n=6)[1].
In vivo
Human Urotensin II (U-II) markedly increases total peripheral resistance in anaesthetized non-human primates, a response associated with profound cardiac contractile dysfunction[1].
AliasUrotensin II (114-124), human acetate(251293-28-4 free base)
Chemical Properties
Molecular Weight1448.63
FormulaC66H89N13O20S2
Cas No.
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 10 mM
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.6903 mL3.4515 mL6.9031 mL34.5154 mL
5 mM0.1381 mL0.6903 mL1.3806 mL6.9031 mL
10 mM0.0690 mL0.3452 mL0.6903 mL3.4515 mL

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