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Ulinastatin

Catalog No. T9268 CAS 80449-31-6

Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.

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Ulinastatin, CAS 80449-31-6

Pack Size	Availability	Price/USD
5 mg	In stock	$ 39.00
10 mg	In stock	$ 68.00
25 mg	In stock	$ 143.00
50 mg	In stock	$ 228.00
100 mg	In stock	$ 372.00
200 mg	In stock	$ 549.00
500 mg	In stock	$ 869.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.

Molecular Weight	N/A
Formula	C13H16O3
CAS No.	80449-31-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 5.5 mg/ml, Sonification is recommended

References and Literature

1. Nakahama H , Kuribayashi K , Sugita M , et al. Cytoprotective effect of ulinastatin, a Kunitz-type protease inhibitor, on hypoxic injury in L2 cells treated with antimycin A via stabilization of lysosomal fragility.[J]. Pulmonary Pharmacology & Therapeutics, 1999, 12(1):1-6. 2. Li S T , Dai Q , Zhang S X , et al. Ulinastatin attenuates LPS-induced inflammation in mouse macrophage RAW264.7 cells by inhibiting the JNK/NF-κB signaling pathway and activating the PI3K/Akt/Nrf2 pathway[J]. Acta Pharmacologica Sinica, 2018.

Citations

1. Bu C, Wang R, Wang Y, et al. Taraxasterol Inhibits Hyperactivation of Macrophages to Alleviate the Sepsis-induced Inflammatory Response of ARDS Rats. Cell Biochemistry and Biophysics. 2022: 1-8.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ulinastatin 80449-31-6 Others inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.