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TrkA-IN-1

Catalog No. T13208 CAS 1680179-43-4

TrkA-IN-1 is a potent and selective inhibitor of Tropomyosin-related kinase A (TrkA) (IC50: 99 nM in a cell-based assay) with analgesic activity.

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TrkA-IN-1, CAS 1680179-43-4

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	TrkA-IN-1 is a potent and selective inhibitor of Tropomyosin-related kinase A (TrkA) (IC50: 99 nM in a cell-based assay) with analgesic activity.
Targets&IC50	TrkC:25 μM, TrkA:99 nM, TrkB:81 μM

Molecular Weight	392.45
Formula	C25H20N4O
CAS No.	1680179-43-4

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Su HP , et al. Structural characterization of nonactive site, TrkA-selective kinase inhibitors. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E297-E306.

Related Products

Related compounds with same targets

3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one LOXO-195 ALE-0540 LM22A-4 Larotrectinib BMS-754807 PF-06737007 Trk-IN-4

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

TrkA-IN-1 1680179-43-4 蛋白酪氨酸激酶 Trk receptor TrkA IN 1 TrkAIN1 Inhibitor inhibitor inhibit

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