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TMRE

Catalog No. T19072 CAS 115532-52-0

Synonyms: Tetramethylrhodamine ethyl ester perchlorate

TMRE (Tetramethylrhodamine ethyl ester perchlorate) is a mitochondria specific dye (λex: 550 nm, λem: 575 nm).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

TMRE, CAS 115532-52-0

Pack Size	Availability	Price/USD
5 mg	In stock	$ 42.00
10 mg	In stock	$ 58.00
25 mg	In stock	Inquiry
50 mg	In stock	Inquiry
1 mL * 10 mM (in DMSO)	In stock	$ 47.00

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Purity: 95%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

TMRE (Tetramethylrhodamine ethyl ester perchlorate) is a mitochondria specific dye (λex: 550 nm, λem: 575 nm).

In vitro

Multidirectional dynamic movement of TMRE is observed in epithelial cells and bidirectional dynamic movement is seen in the superficial cortical fiber cells of live bovine lenses. In the epithelium, the movement of TMRE fluorescence is up to 5 μm/min whereas in the superficial cortex the observed movement is up to 18.5 μm/min. The movement of TMRE fluorescence is abolished with the treatment of the uncoupler, carbonyl cyanide m-chlorophenylhydrazone [2].

Synonyms	Tetramethylrhodamine ethyl ester perchlorate
Molecular Weight	514.95
Formula	C26H27ClN2O7
CAS No.	115532-52-0

Storage

keep away from direct sunlight

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 27.78 mg/mL (53.95 mM), Sonication is recommended.

References and Literature

1. Crowley LC, et al. Measuring Mitochondrial Transmembrane Potential by TMRE Staining. Cold Spring Harb Protoc. 2016 Dec 1;2016(12):pdb.prot087361. 2. Bantseev V, et al. Confocal laser scanning microscopy imaging of dynamic TMRE movement in the mitochondria of epithelial and superficial cortical fiber cells of bovine lenses. Mol Vis. 2005 Jul 14;11:518-23.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

TMRE 115532-52-0 Others Tetramethylrhodamine ethyl ester Tetramethylrhodamine ethyl ester Perchlorate Inhibitor inhibit Tetramethylrhodamine ethyl ester perchlorate inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.