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Rezafungin

Name: Rezafungin
Brand: TargetMol
SKU: T12732
Price: 189 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12732Cas No. 1396640-59-7

Alias SP-3025, CD101, Biafungin

Rezafungin (SP-3025) is a broad-spectrum and long-lasting echinocandin with potent antifungal activity against Candida, Aspergillus and Pneumocystis.

Rezafungin

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Purity: 99.87%

Catalog No. T12732Alias SP-3025, CD101, BiafunginCas No. 1396640-59-7

Rezafungin (SP-3025) is a broad-spectrum and long-lasting echinocandin with potent antifungal activity against Candida, Aspergillus and Pneumocystis.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$189	In Stock	-
2 mg	$279	In Stock	-
5 mg	$398	In Stock	-
10 mg	$592	In Stock	-
25 mg	$947	In Stock	-
50 mg	$1,280	In Stock	-
100 mg	$1,730	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$831	In Stock	-

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.87%

Appearance:Solid

Color:White

Resource Download

COA MS HPLC LCMS

Product Introduction

Bioactivity

Description	Rezafungin (SP-3025) is a broad-spectrum and long-lasting echinocandin with potent antifungal activity against Candida, Aspergillus and Pneumocystis.
Targets&IC50	C. insconspicua:0.06 µg/mL (MIC), C. pulcherrima:0.03 µg/mL (MIC), C. krusei:0.033 µg/Ml (MIC), C. tropicalis:0.03 µg/mL (MIC), C. albicans:0.022 µg/mL (MIC), C. guilliermondii:1 µg/mL (MIC), C. dubliniensis:0.06 µg/mL (MIC), C. glabrata:0.044 µg/mL (MIC), C. auris:0.153 µg/mL (MIC), C. parapsilosis sensu stricto:1.26 µg/mL (MIC), C. lusitaniae:0.12 µg/mL (MIC), C. kefyr:0.06 µg/mL (MIC)
In vivo	Intraperitoneal injection of 1 mg/kg of Rezafungin once daily for 6 days in mice showed effective in vivo prevention of Pneumocystis spp., significantly reducing nuclear and asci burden in a C3H/HeN mouse infection model[1].
Synonyms	SP-3025, CD101, Biafungin

Chemical Properties

Molecular Weight	1226.39
Formula	C₆₃H₈₅N₈O₁₇
Cas No.	1396640-59-7
Smiles	O=C1N2[C@](C(=O)N[C@H](OCC[N+](C)(C)C)[C@H](O)C[C@H](NC(=O)C3=CC=C(C=C3)C4=CC=C(C=C4)C5=CC=C(OCCCCC)C=C5)C(=O)N[C@@]([C@@H](C)O)(C(=O)N6[C@](C(=O)N[C@@]([C@@H]([C@@H](O)C7=CC=C(O)C=C7)O)(C(=O)N[C@]1([C@@H](C)O)[H])[H])(C[C@@H](O)C6)[H])[H])([C@@H](O)[C@@H](C)C2)[H]
Relative Density.	no data available

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 65 mg/mL (53 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.8154 mL	4.0770 mL	8.1540 mL	40.7701 mL
5 mM	0.1631 mL	0.8154 mL	1.6308 mL	8.1540 mL
10 mM	0.0815 mL	0.4077 mL	0.8154 mL	4.0770 mL
20 mM	0.0408 mL	0.2039 mL	0.4077 mL	2.0385 mL
50 mM	0.0163 mL	0.0815 mL	0.1631 mL	0.8154 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc