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Methylisothiazolinone hydrochloride

Catalog No. T28029 CAS 26172-54-3

Synonyms: N-Methylisothiazolin-3-one, MI, KB-838, Methylisothiazolinone HCl

Methylisothiazolinone is a powerful synthetic biocide and preservative.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Methylisothiazolinone hydrochloride Chemical Structure

Methylisothiazolinone hydrochloride, CAS 26172-54-3

Pack Size	Availability	Price/USD	Quantity
50 mg	5 days	Inquiry
100 mg	5 days	Inquiry

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Methylisothiazolinone is a powerful synthetic biocide and preservative.

Synonyms	N-Methylisothiazolin-3-one, MI, KB-838, Methylisothiazolinone HCl
Molecular Weight	151.62
Formula	C4H6ClNOS
CAS No.	26172-54-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Hill H, Goldenberg A, Golkar L, Beck K, Williams J, Jacob SE. Pre-Emptive Avoidance Strategy (P.E.A.S.) - addressing allergic contact dermatitis in pediatric populations. Expert Rev Clin Immunol. 2016;12(5):551-61. doi: 10.1586/1744666X.2016.1142373. Epub 2016 Feb 29. Review. PubMed PMID: 26764601. 2. Schwensen JF, Bregnbak D, Johansen JD. Recent trends in epidemiology, sensitization and legal requirements of selected relevant contact allergens. Expert Rev Clin Immunol. 2016;12(3):289-300. doi: 10.1586/1744666X.2016.1120159. Epub 2015 Nov 30. Review. PubMed PMID: 26563976. 3. Aerts O, Goossens A, Giordano-Labadie F. Contact allergy caused by methylisothiazolinone: the Belgian-French experience. Eur J Dermatol. 2015 May-Jun;25(3):228-33. doi: 10.1684/ejd.2015.2608. Review. PubMed PMID: 26412037. 4. Eubel J, Diepgen TL, Weisshaar E. [Allergic diseases in the genital area]. Hautarzt. 2015 Jan;66(1):45-52. doi: 10.1007/s00105-014-3561-1. Review. German. PubMed PMID: 25532902.

Dose Conversion

You can also refer to dose conversion for different animals. More

In vivo Formulation Calculator (Clear solution)

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Step Two: Enter the in vivo formulation

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Molarity Calculator

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Reconstitution Calculation

Molecular Weight Calculator

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Mass of a compound required to prepare a solution of known volume and concentration
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See Example

An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Methylisothiazolinone hydrochloride 26172-54-3 N-Methylisothiazolin-3-one KB 838 MI Methylisothiazolinone Hydrochloride KB-838 Methylisothiazolinone HCl KB838 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.