Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Manitimus is a potent immunosuppressive drug, and is an inhibitor of dehydroorotate dehydrogenase,.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Manitimus is a potent immunosuppressive drug, and is an inhibitor of dehydroorotate dehydrogenase,. |
In vivo | Administering Manitimus (15 mg/kg, p.o.) significantly reduces both the neointimal area and the percentage of stenosis in comparison to control rats, while also mitigating the enhancement of intimal and medial cross-sectional area and medial wall thickness in vein grafts caused by CMV infection[2]. Additionally, a dose-dependent relationship is observed in Manitimus-treated rats, with mean survival extending to 15.7 days at a 5 mg/kg dose, 19.1 days at a 10 mg/kg dose, and reaching 25.4 days at a 20 mg/kg dose, demonstrating a differential effect based on the dosage administered[1]. |
Synonyms | FK778 |
Molecular Weight | 308.26 |
Formula | C15H11F3N2O2 |
CAS No. | 202057-76-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Manitimus 202057-76-9 Others FK778 FK-778 FK 778 inhibitor inhibit