Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 6-8 weeks | $ 289.00 | |
25 mg | 6-8 weeks | $ 954.00 | |
50 mg | 6-8 weeks | $ 1,240.00 | |
100 mg | 6-8 weeks | $ 1,740.00 | |
1 mL * 10 mM (in DMSO) | 6-8 weeks | $ 391.00 |
Description | MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells. |
In vitro | MIR96-IN-1 inhibits Drosha cleavage of pri-miR-96, as evidenced by an increase in the levels of pri-miR-96 and a reduction in levels of pre- and mature miR-96 in treated cells, as expected if MIR96-IN-1 binds to the Drosha site. MIR96-IN-1 efficiently and selectively silences production of miR-96 at 40 μM while not affecting miR-182 or -183. MIR96-IN-1 inhibits biogenesis of its target precursor miRNA to varying extents: MIR96-IN-1 reduces the expression level of miR-96 by 90% at 40 μM [1]. |
Molecular Weight | 588.79 |
Formula | C33H48N8O2 |
CAS No. | 1311982-88-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (169.84 mM)
You can also refer to dose conversion for different animals. More
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MIR96-IN-1 1311982-88-3 Immunology/Inflammation MALT MIR96 IN 1 MIR-96-IN-1 MIR96IN1 inhibitor inhibit