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Lansoprazole sulfide

Catalog No. T21128 CAS 103577-40-8

Synonyms: Lansoprazole impurity C, AG-1777, EC 600-451-9, H 225/18, K-1252

Lansoprazole sulfide is an impurity of Lansoprazole, which is a gastric pump inhibitor.

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Lansoprazole sulfide, CAS 103577-40-8

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1 g	5 days	$ 310.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Lansoprazole sulfide is an impurity of Lansoprazole, which is a gastric pump inhibitor.

Synonyms	Lansoprazole impurity C, AG-1777, EC 600-451-9, H 225/18, K-1252
Molecular Weight	353.36
Formula	C16H14F3N3OS
CAS No.	103577-40-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Soluble

References and Literature

1. Mdanda S, Baijnath S, Shobo A, Singh SD, Maguire GEM, Kruger HG, Arvidsson PI, Naicker T, Govender T. Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent. Biomed Chromatogr. 2017 Dec;31(12). doi: 10.1002/bmc.4035. Epub 2017 Jul 13. PubMed PMID: 28623874. 2. Rybniker J, Vocat A, Sala C, Busso P, Pojer F, Benjak A, Cole ST. Lansoprazole is an antituberculous prodrug targeting cytochrome bc1. Nat Commun. 2015 Jul 9;6:7659. doi: 10.1038/ncomms8659. PubMed PMID: 26158909; PubMed Central PMCID: PMC4510652. 3. Pearce RE, Rodrigues AD, Goldstein JA, Parkinson A. Identification of the human P450 enzymes involved in lansoprazole metabolism. J Pharmacol Exp Ther. 1996 May;277(2):805-16. PubMed PMID: 8627562. 4. Landes BD, Petite JP, Flouvat B. Clinical pharmacokinetics of lansoprazole. Clin Pharmacokinet. 1995 Jun;28(6):458-70. Review. PubMed PMID: 7656504.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Lansoprazole sulfide 103577-40-8 Lansoprazole impurity C AG-1777 EC 600-451-9 AG1777 AG 1777 Lansoprazole Sulfide H 225/18 K 1252 K1252 K-1252 inhibitor inhibit

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