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L-97-1

Catalog No. T24384 CAS 770703-20-3

Synonyms: L97-1, L 97-1

L-97-1 is an antagonist of the adenosine A1 receptor.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

L-97-1, CAS 770703-20-3

Pack Size	Availability	Price/USD
25 mg	10-14 weeks	$ 2,420.00
50 mg	10-14 weeks	$ 3,180.00
100 mg	10-14 weeks	$ 4,300.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

L-97-1 is an antagonist of the adenosine A1 receptor.

Synonyms	L97-1, L 97-1
Molecular Weight	518.65
Formula	C29H38N6O3
CAS No.	770703-20-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Wilson CN, Vance CO, Lechner MG, Matuschak GM, Lechner AJ. Adenosine A1 receptor antagonist, L-97-1, improves survival and protects the kidney in a rat model of cecal ligation and puncture induced sepsis. Eur J Pharmacol. 2014 Oct 5;740:346-52. doi: 10.1016/j.ejphar.2014.07.012. Epub 2014 Jul 18. PubMed PMID: 25041842; PubMed Central PMCID: PMC4147868. 2. Cullen L, Parsonage WA, Greenslade J, Lamanna A, Hammett CJ, Than M, Tate J, Kalinowski L, Ungerer JP, Chu K, Brown A. Delta troponin for the early diagnosis of AMI in emergency patients with chest pain. Int J Cardiol. 2013 Oct 3;168(3):2602-8. doi: 10.1016/j.ijcard.2013.03.044. Epub 2013 Apr 10. PubMed PMID: 23582689. 3. Wilson CN, Vance CO, Doyle TM, Brink DS, Matuschak GM, Lechner AJ. A novel post-exposure medical countermeasure L-97-1 improves survival and acute lung injury following intratracheal infection with Yersinia pestis. Innate Immun. 2012 Jun;18(3):373-89. doi: 10.1177/1753425911411595. Epub 2011 Aug 23. PubMed PMID: 21862597; PubMed Central PMCID: PMC3362682. 4. Rehman S, Lloyd-Jones DM, Martinez-Rumayor A, Januzzi JL. Inflammatory markers, amino-terminal pro-brain natriuretic peptide, and mortality risk in dyspneic patients. Am J Clin Pathol. 2008 Aug;130(2):305-11. doi: 10.1309/L7BP57F7UF7YNYKX. PubMed PMID: 18628102.

Citations

1. Li M, Yan Y, Zhang X, et al. Scaffold compound L971 exhibits anti‐inflammatory activities through inhibition of JAK/STAT and NFκB signalling pathways. Journal of Cellular and Molecular Medicine. 2021

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

L-97-1 770703-20-3 L97-1 L971 L 97 1 L 97-1 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.