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Jarin-1

Catalog No. T15608 CAS 1212704-51-2

Jarin-1 is a jasmonic acid-amido synthetase (JAR1) inhibitor (IC50: 3.8 μM). Jarin-1 specific suppresses bioactive JA biosynthesis in Arabidopsis and other plants.

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Jarin-1, CAS 1212704-51-2

Pack Size	Availability	Price/USD
1 mg	In stock	$ 72.00
5 mg	In stock	$ 197.00
10 mg	In stock	$ 328.00
25 mg	In stock	$ 558.00
50 mg	In stock	$ 788.00
100 mg	In stock	$ 1,120.00
1 mL * 10 mM (in DMSO)	In stock	$ 213.00

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Purity: 99.8%

Biological Description

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Description

Jarin-1 is a jasmonic acid-amido synthetase (JAR1) inhibitor (IC50: 3.8 μM). Jarin-1 specific suppresses bioactive JA biosynthesis in Arabidopsis and other plants.

In vitro

MeJA + Jarin-1 treatment caused an upregulation of FaANR and associated transcription factors such as FabHLH33 and FaMYB9/11 along with FaJMT and FaJAR1.2. JA-responsive elements in the promoter regions of FaMYB1/9/10/11 genes are found. The proanthocyanidin (PA) content was higher in Jarin-1- and MeJA + Jarin-1-treated than in MeJA-treated fruits. PA biosynthesis-related genes can be upregulated by the application of Jarin-1 to MeJA-treated fruit, thus increasing PA accumulation in strawberry. A higher redness of strawberry fruit skin and anthocyanin content in MeJA-treated fruits with respect to Jarin-1-treated ones concomitant with an upregulation of FaANS and FaUFGT genes is found [1].

Molecular Weight	471.55
Formula	C28H29N3O4
CAS No.	1212704-51-2

Storage

keep away from direct sunlight

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 30.6 mg/mL (64.9 mM), Sonication is recommended.

References and Literature

1. Delgado LD, et al. Application of a JA-Ile Biosynthesis Inhibitor to Methyl Jasmonate-Treated Strawberry Fruit Induces Upregulation of Specific MBW Complex-Related Genes and Accumulation of Proanthocyanidins. Molecules. 2018 Jun 13;23(6). pii: E1433. 2. Meesters C, et al. A chemical inhibitor of jasmonate signaling targets JAR1 in Arabidopsis thaliana. Nat Chem Biol. 2014 Oct;10(10):830-6.

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Keywords

Jarin-1 1212704-51-2 Others Jarin 1 Jarin1 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.