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Isocupressic acid

Name: Isocupressic acid
Brand: TargetMol
SKU: TN4277
Rating: 4.5 (1 reviews)

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Catalog No. TN4277Cas No. 1909-91-7

Alias (+)-Isocupressic acid

Isocupressic acid ((+)-Isocupressic acid) is an abortifacient isolated from pine needles and bark that blocks progesterone production in bovine corpus luteum cells.

Isocupressic acid

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Purity: 98%

Catalog No. TN4277Alias (+)-Isocupressic acidCas No. 1909-91-7

Isocupressic acid ((+)-Isocupressic acid) is an abortifacient isolated from pine needles and bark that blocks progesterone production in bovine corpus luteum cells.

Pack Size	Price	Availability	Quantity
1 mg	$677	7-10 days
5 mg	$1,489	7-10 days

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Purity:98%

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COA HPLC

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Product Introduction

Bioactivity

Description	Isocupressic acid ((+)-Isocupressic acid) is an abortifacient isolated from pine needles and bark that blocks progesterone production in bovine corpus luteum cells.
In vitro	Isocupressic acid inhibits basal and ovine luteinizing hormone (oLH) stimulating secretion of progesterone in bovine luteal cells and inhibits progesterone production by blocking oLH and cAMP actions at the cellular level of luteal cells. [1]
Alias	(+)-Isocupressic acid

Chemical Properties

Molecular Weight	320.47
Formula	C₂₀H₃₂O₃
Cas No.	1909-91-7
Smiles	C[C@@]12[C@]([C@](C(O)=O)(C)CCC1)(CCC(=C)[C@@H]2CC/C(=C/CO)/C)[H]
Relative Density.	1.06 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PKAIsocupressic acidCYP17cAMP