Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GSK180 is a selective competitive inhibitor of kynurenine 3-monooxygenase (KMO; IC50: ~6 nM), an enzyme involved in tryptophan metabolism.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 86.00 | |
5 mg | 5 days | $ 140.00 | |
1 mL * 10 mM (in DMSO) | 5 days | $ 133.00 |
Description | GSK180 is a selective competitive inhibitor of kynurenine 3-monooxygenase (KMO; IC50: ~6 nM), an enzyme involved in tryptophan metabolism. |
Targets&IC50 | KMO:~6 nM |
In vitro | GSK180 inhibits endogenous KMO activity in primary human hepatocytes (IC50=2.6 μM) and it also inhibits rat KMO slightly less potently than the human enzyme (IC50=7 μM). |
In vivo | GSK180 is fit for i.v. management [1]. |
Molecular Weight | 276.07 |
Formula | C10H7Cl2NO4 |
CAS No. | 1799725-26-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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GSK180 1799725-26-0 Metabolism Hydroxylase GSK 180 GSK-180 inhibitor inhibit