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Eicosatetraynoic acid

Catalog No. T11169 CAS 1191-85-1

Synonyms: ETYA

Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 μM. Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively).

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Eicosatetraynoic acid Chemical Structure

Eicosatetraynoic acid, CAS 1191-85-1

Pack Size	Availability	Price/USD
5 mg	4-5 weeks	$ 133.00
10 mg	4-5 weeks	$ 240.00
25 mg	4-5 weeks	$ 568.00
50 mg	4-5 weeks	$ 998.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 μM. Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively).
Targets&IC50	COX:8 μM (ID50)

Synonyms	ETYA
Molecular Weight	296.4
Formula	C20H24O2
CAS No.	1191-85-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 2 mg/mL (6.75 mM), Sonification is recommended.

References and Literature

1. Hammarström S, et al. Selective inhibition of platelet n-8 lipoxygenase by 5,8,11-eicosatriynoic acid. Biochim Biophys Acta. 1977 Jun 22;487(3):517-9. 2. Kliewer SA, et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell. 1995 Dec 1;83(5):813-9.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Eicosatetraynoic acid 1191-85-1 Immunology/Inflammation Neuroscience COX ETYA inhibitor inhibit

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