Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DO1 (Disperse Orange 1) is an anti-amyloid agent which potently delays both seeded and non-seeded Aβ42 polymerization at substoichiometric concentrations
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 50.00 | |
10 mg | In stock | $ 72.00 | |
25 mg | In stock | $ 103.00 | |
50 mg | In stock | $ 198.00 | |
100 mg | In stock | $ 298.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 64.00 |
Description | DO1 (Disperse Orange 1) is an anti-amyloid agent which potently delays both seeded and non-seeded Aβ42 polymerization at substoichiometric concentrations |
In vivo | DO1 disrupts preformed fibrillar assemblies of synthetic Aβ42 peptides and decreases the seeding activity of Aβ aggregates from brain extracts of AD transgenic mice.?DO1 also reduced the size and abundance of diffuse Aβ plaques and decreased neuroinflammation-related gene expression changes in brains of 5xFAD transgenic mice[1]. |
Synonyms | Disperse Orange 1 |
Molecular Weight | 318.33 |
Formula | C18H14N4O2 |
CAS No. | 2581-69-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.18 mg/mL (10 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
DO1 2581-69-3 Others Disperse Orange 1 DO-1 DO 1 inhibitor inhibit