Powder: -20°C for 3 years | In solvent: -80°C for 1 year
D-3263 is an agonist of transient receptor potential melatonin member 8 (TRPM8) with potential antitumor activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,670.00 | |
50 mg | 6-8 weeks | $ 2,180.00 | |
100 mg | 6-8 weeks | $ 2,800.00 |
Description | D-3263 is an agonist of transient receptor potential melatonin member 8 (TRPM8) with potential antitumor activity. |
In vitro | D-3263 induces calcium flux and cell death in cells expressing TRPM8 in vitro. |
In vivo | D-3263 alone (50 or 100 mg / kg / d) or in combination with finasteride (10 mg / kg / d) can lead to decreased prostate hyperplasia in rats, with evidence of dose response. The highest dose of TRPM8 agonist D-3263 combined with finasteride caused lower prostate weight than the highest dose of D-3263 or finasteride alone, indicating a potential additive effect. |
Molecular Weight | 373.49 |
Formula | C21H31N3O3 |
CAS No. | 947257-66-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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D-3263 947257-66-1 Others D 3263 D3263 inhibitor inhibit