Powder: -20°C for 3 years
In solvent: -80°C for 2 years
3344 is an inhibitor of KRAS-effector interactions,with an affnity of 126nm.
Description | 3344 is an inhibitor of KRAS-effector interactions,with an affnity of 126nm. |
In vitro | In vitro competition studies of 3344 binding to KRAS-G12V in waterLOGSY NMR show the anti-RAS scFv inhibits 3344 binding to KRAS. In view of the in vitro inhibition by the anti-RAS scFv of 3344 binding to RASand because the iDAb RAS interferes with BRET signal in cells, 3344 was used for valida?tion of the BRET2 toolbox for RAS-effector PPI inhibitors. |
Molecular Weight | 390.47 |
Formula | C24H26N2O3 |
CAS No. | 2368246-78-8 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Compound 3344 2368246-78-8 G蛋白偶联受体 MAPK信号通路 Ras Inhibitor inhibitor inhibit