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Chloramine-T

Name: Chloramine-T
Brand: TargetMol
SKU: T0669
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0669Cas No. 127-65-1

Alias Chlorozone, Chlorasan, Chloralone

Chloramine-T (Chloralone) is a N-chlorinated, and N-deprotonated sulfonamide, used as a biocide and a mild disinfectant.

Chloramine-T

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Purity: 99.64%

Catalog No. T0669Alias Chlorozone, Chlorasan, ChloraloneCas No. 127-65-1

Chloramine-T (Chloralone) is a N-chlorinated, and N-deprotonated sulfonamide, used as a biocide and a mild disinfectant.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.64%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Chloramine-T AI Summary

Chloramine-T demonstrates antiviral activity against SARS-CoV-2 by inhibiting viral cytotoxicity in both Caco-2 and VERO-6 cells at a concentration of 10 µM after 48 hours of exposure. Additionally, it shows inhibitory activity against the SARS-CoV-2 3CL-Pro protease at a concentration of 20 µM, with an inhibition percentage of 12.66%, as measured by a FRET-based assay. Despite varying inhibitory percentages in different assays, the compound consistently exhibits potential for antiviral activity against SARS-CoV-2..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Chloramine-T (Chloralone) is a N-chlorinated, and N-deprotonated sulfonamide, used as a biocide and a mild disinfectant.
Synonyms	Chlorozone, Chlorasan, Chloralone

Chemical Properties

Molecular Weight	227.65
Formula	C₇H₇ClNNaO₂S
Cas No.	127-65-1
Smiles	O.[Na+].Cc1ccc(cc1)S(=O)(=O)[N-]Cl
Relative Density.	1.401 g/cm3 at 20℃

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 180.11 mM, Sonication is recommended.

DMSO: 250 mg/mL (1098.18 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2.5 mg/mL (10.98 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.3927 mL	21.9635 mL	43.9271 mL	219.6354 mL
5 mM	0.8785 mL	4.3927 mL	8.7854 mL	43.9271 mL
10 mM	0.4393 mL	2.1964 mL	4.3927 mL	21.9635 mL
20 mM	0.2196 mL	1.0982 mL	2.1964 mL	10.9818 mL
50 mM	0.0879 mL	0.4393 mL	0.8785 mL	4.3927 mL
100 mM	0.0439 mL	0.2196 mL	0.4393 mL	2.1964 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc