Powder: -20°C for 3 years
In solvent: -80°C for 2 years
GRKs-IN-1 has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50: 130 nM) and GRK5 (IC50: 7.1 μM).
Description | GRKs-IN-1 has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50: 130 nM) and GRK5 (IC50: 7.1 μM). |
Targets&IC50 | GRK5:7.1 μM, GRK2:30 nM |
In vitro | GRKs-IN-1 (Compound 14as) is a derivative 14as of paroxetine, shows a 100-fold improvement in cardiomyocyte contractility assays over paroxetine. |
Synonyms | GRK2-IN-1 |
Molecular Weight | 452.48 |
Formula | C24H25FN4O4 |
CAS No. | 2055990-90-2 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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CCG258208 2055990-90-2 G蛋白偶联受体 GRK GRK2-IN-1 CCG-258208 Inhibitor inhibitor inhibit