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Amfenac

Catalog No. T1720L   CAS 51579-82-9
Synonyms: NSC309467, NSC-309467, NSC 309467

Amfenac promotes apoptosis in ARPE-19 cell culture.

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Amfenac Chemical Structure
Amfenac, CAS 51579-82-9
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Amfenac promotes apoptosis in ARPE-19 cell culture.
Synonyms NSC309467, NSC-309467, NSC 309467
Molecular Weight 255.27
Formula C15H13NO3
CAS No. 51579-82-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Argun M, Tök L, Uğuz AC, Çelik Ö, Tök ÖY, Naziroğlu M. Melatonin and amfenac modulate calcium entry, apoptosis, and oxidative stress in ARPE-19 cell culture exposed to blue light irradiation (405 nm). Eye (Lond). 2014 Jun;28(6):752-60. doi: 10.1038/eye.2014.50. Epub 2014 Mar 7. PubMed PMID: 24603419; PubMed Central PMCID: PMC4058615. 2. Chastain JE, Sanders ME, Curtis MA, Chemuturi NV, Gadd ME, Kapin MA, Markwardt KL, Dahlin DC. Distribution of topical ocular nepafenac and its active metabolite amfenac to the posterior segment of the eye. Exp Eye Res. 2016 Apr;145:58-67. doi: 10.1016/j.exer.2015.10.009. Epub 2015 Oct 22. PubMed PMID: 26474497. 3. Yanni SE, Clark ML, Yang R, Bingaman DP, Penn JS. The effects of nepafenac and amfenac on retinal angiogenesis. Brain Res Bull. 2010 Feb 15;81(2-3):310-9. doi: 10.1016/j.brainresbull.2009.10.018. Epub 2009 Nov 6. PubMed PMID: 19897019; PubMed Central PMCID: PMC2815002. 4. Hiranuma T, Kato S, Hachisu M. Analgesic action of amfenac Na, a non-steroidal anti-inflammatory agent. J Pharmacobiodyn. 1988 Sep;11(9):612-9. PubMed PMID: 3265150.

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Keywords

Amfenac 51579-82-9 NSC309467 NSC-309467 NSC 309467 inhibitor inhibit

 

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