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1-Methyl-2-pentyl-4(1H)-quinolinone

🥰Excellent
Catalog No. TN1175Cas No. 22048-98-2
Alias 1-methyl-2-pentylquinolin-4-one

1-Methyl-2-pentyl-4(1H)-quinolinone, a low toxic natural product containing a quinoline structure, is a specific inhibitor of Plasmodium falciparum type II NADH dehydrogenase (PfNDH2), significantly inhibits Plasmodium falciparum development in the mosquito stage and blocks malaria transmission.

1-Methyl-2-pentyl-4(1H)-quinolinone

1-Methyl-2-pentyl-4(1H)-quinolinone

🥰Excellent
Catalog No. TN1175Alias 1-methyl-2-pentylquinolin-4-oneCas No. 22048-98-2
1-Methyl-2-pentyl-4(1H)-quinolinone, a low toxic natural product containing a quinoline structure, is a specific inhibitor of Plasmodium falciparum type II NADH dehydrogenase (PfNDH2), significantly inhibits Plasmodium falciparum development in the mosquito stage and blocks malaria transmission.
Pack SizePriceAvailabilityQuantity
1 mg$81In Stock
5 mg$198In Stock
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Product Introduction

Bioactivity
Description
1-Methyl-2-pentyl-4(1H)-quinolinone, a low toxic natural product containing a quinoline structure, is a specific inhibitor of Plasmodium falciparum type II NADH dehydrogenase (PfNDH2), significantly inhibits Plasmodium falciparum development in the mosquito stage and blocks malaria transmission.
Synonyms1-methyl-2-pentylquinolin-4-one
Chemical Properties
Molecular Weight229.32
FormulaC15H19NO
Cas No.22048-98-2
SmilesO=C1C=C(N(C=2C=CC=CC12)C)CCCCC
Relative Density.1.032 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight,store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 40 mg/mL (174.43 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.3607 mL21.8036 mL43.6072 mL218.0359 mL
5 mM0.8721 mL4.3607 mL8.7214 mL43.6072 mL
10 mM0.4361 mL2.1804 mL4.3607 mL21.8036 mL
20 mM0.2180 mL1.0902 mL2.1804 mL10.9018 mL
50 mM0.0872 mL0.4361 mL0.8721 mL4.3607 mL
100 mM0.0436 mL0.2180 mL0.4361 mL2.1804 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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Keywords

1-Methyl-2-pentyl-4(1H)-quinolinone1Methyl2pentyl4(1H)quinolinone1 Methyl 2 pentyl 4(1H) quinolinone
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