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(Arg)9 TFA (143413-47-2 free base)

Catalog No. TP1079 CAS 2283335-13-5

Synonyms: Nona-L-arginine (TFA), (Arg)9 TFA, Peptide R9 (TFA)

(Arg)9 TFA (Peptide R9 TFA) is a cell-penetrating peptide. (Arg)9 TFA (Nona-L-arginine TFA) exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model.

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(Arg)9 TFA (143413-47-2 free base) Chemical Structure

(Arg)9 TFA (143413-47-2 free base), CAS 2283335-13-5

Pack Size	Availability	Price/USD
1 mg	In stock	$ 139.00
2 mg	In stock	$ 216.00
5 mg	In stock	$ 422.00
10 mg	In stock	$ 613.00
25 mg	In stock	$ 957.00
50 mg	In stock	$ 1,290.00
100 mg	In stock	$ 1,730.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	(Arg)9 TFA (Peptide R9 TFA) is a cell-penetrating peptide. (Arg)9 TFA (Nona-L-arginine TFA) exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model.
Targets&IC50	Neuroprotection:0.78 μM (IC50)
In vivo	(Arg)9) (D-isoform) is neuroprotective in rat stroke models. (Arg)9) is highly neuroprotective, with efficacy increasing with increasing arginine content. It has the capacity to reduce glutamic acid-induced neuronal calcium influx and requires heparan sulfate preotoglycan-mediated endocytosis to induce a neuroprotective effect[2]. (Arg)9) (D-isoform) administered intravenously at a dose of 1000 nmol/kg 30 min after permanent middle cerebral artery occlusion (MCAO) reduces infarct volume[3].

Synonyms	Nona-L-arginine (TFA), (Arg)9 TFA, Peptide R9 (TFA)
Molecular Weight	1537.71
Formula	C56H111F3N36O12
CAS No.	2283335-13-5

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 10 mM

DMSO: Insoluble

References and Literature

1. Meloni BP, et al. The neuroprotective efficacy of cell-penetrating peptides TAT, penetratin, Arg-9, and Pep-1 in glutamic acid, kainic acid, and in vitro ischemia injury models using primary cortical neuronal cultures. Cell Mol Neurobiol. 2014 Mar;34(2):173-81.

Related compound libraries

This product is contained In the following compound libraries：

Peptide Compound Library NO PAINS Compound Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

(Arg)9 TFA (143413-47-2 free base) 2283335-13-5 Others (Arg)9 TFA (143413 47 2 free base) Peptide R-9 inhibit Inhibitor 143413-47-2 Nona-L-arginine (Arg)9 TFA (143413472 free base) (Arg)9 143413-47-2 free base Peptide R 9 Nona-L-arginine (TFA) (Arg)9 TFA Peptide R9 Peptide R9 (TFA) inhibitor

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