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CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc)

Catalog No. TMPJ-00341
Synonyms: TNFRSF8, Ki-1 antigen, CD30, CD30L receptor, Tumor necrosis factor receptor superfamily member 8, Lymphocyte activation antigen CD30

CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P28908.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 79.00
50 μg 5 days $ 184.00
500 μg 5 days $ 1,390.00
1 mg 5 days $ 1,980.00
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Biological Description
Technical Params
Product Properties
Description CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P28908.
Species Human
Expression System HEK293 Cells
Tag C-hFc
Accession Number P28908
Synonyms TNFRSF8, Ki-1 antigen, CD30, CD30L receptor, Tumor necrosis factor receptor superfamily member 8, Lymphocyte activation antigen CD30
Amino Acid Phe19-Lys379
Construction Phe19-Lys379
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 90-120 KDa (reducing condition)
Endotoxin < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL). CD30 is also a biomarker used for targeted therapy by an antibody–drug conjugate.

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Keywords

CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc) CD 30 CD-30 TNFRSF8 Ki-1 antigen CD30 TNFRSF 8 CD30L receptor Tumor necrosis factor receptor superfamily member 8 TNFRSF-8 Lymphocyte activation antigen CD30 recombinant recombinant-proteins proteins protein

 

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