Powder: -20°C for 3 years | In solvent: -80°C for 1 year
squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-terminus of Src kinase to UNC119A
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 31.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 113.00 | |
25 mg | In stock | $ 239.00 | |
50 mg | In stock | $ 355.00 | |
100 mg | In stock | $ 527.00 |
Description | squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-terminus of Src kinase to UNC119A |
In vitro | Squarunkin A (2.5 μM, 0.625 μM, 0.078 μM, and 0.01 μM) treatment leads to a concentration-dependent reduction of Src phosphorylation.It does not target the lipoprotein-binding sites of other lipoprotein chaperones, such as PDE6d, AIPL1, and RhoGDI, which bind S-prenylated proteins.?It binds to UNC119 in cell lysate and interferes with Src activation. |
Molecular Weight | 523.55 |
Formula | C25H32F3N5O4 |
CAS No. | 2101958-02-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5.24 mg/mL (10 mM)
You can also refer to dose conversion for different animals. More
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squarunkinA 2101958-02-3 Angiogenesis Others Tyrosine Kinase/Adaptors Src inhibitor inhibit