Powder: -20°C for 3 years | In solvent: -80°C for 1 year
p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor. It suppresses p53-mediated TGF-β1 expression in HK-2 cells and inhibits the activation of caspase-3 by Zika virus (ZIKV) strains. Moreover, p-nitro-Pifithrin-α attenuates steatosis and liver injury in mice subjected to a high-fat diet, mitigating the effects of non-alcoholic fatty liver disease [1] [2] [3] [4].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 110.00 | |
5 mg | 35 days | $ 295.00 | |
10 mg | 35 days | $ 535.00 | |
25 mg | 35 days | $ 1,190.00 |
Description | p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor. It suppresses p53-mediated TGF-β1 expression in HK-2 cells and inhibits the activation of caspase-3 by Zika virus (ZIKV) strains. Moreover, p-nitro-Pifithrin-α attenuates steatosis and liver injury in mice subjected to a high-fat diet, mitigating the effects of non-alcoholic fatty liver disease [1] [2] [3] [4]. |
Molecular Weight | 398.27 |
Formula | C15H16BrN3O3S |
CAS No. | 389850-21-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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p-nitro-Pifithrin-α 389850-21-9 p-nitro-Pifithrin-alpha p nitro Pifithrin α p-nitro-Pifithrin-a pnitroPifithrinα inhibitor inhibit