Dtk Protein, Mouse, Recombinant (hFc)

Name: Dtk Protein, Mouse, Recombinant (hFc)
Brand: TargetMol
SKU: TMPJ-01017
Rating: 4.5 (1 reviews)

(Synonyms: Tyrosine-protein kinase TIF, Tyrosine-protein kinase RSE, Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase DTK, tyro3, TK19-2, Etk2) Copy Product Info

Synonyms: Tyrosine-protein kinase TIF, Tyrosine-protein kinase RSE, Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase DTK, tyro3, TK19-2, Etk2

Catalog No. TMPJ-01017 Copy Product Info

Dtk Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P55144.

Pack Size	Price	USA Stock	Global Stock
10 µg	$35	35 days	35 days
20 µg	$55	35 days	35 days
50 µg	$110	35 days	35 days
100 µg	$192	35 days	35 days
200 µg	$342	35 days	35 days
500 µg	$745	35 days	35 days
1 mg	$1,180	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Dtk Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P55144.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	P55144
Amino Acid	Ala31-Ser418
Construction	Ala31-Ser418
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Tyrosine-protein kinase TIF, Tyrosine-protein kinase RSE, Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase DTK, tyro3, TK19-2, Etk2
Research Background	Dtk, also called Tyro3, belongs to the TAM receptor family of receptor protein tyrosine kinases (RPTKs) composed of three receptors Tyro3, Axl, and Mer. These receptors share a characteristic molecular structure of two immunoglobulin-like and two fibronectin type III repeats and have been best characterized for their roles in immune regulation, fertility, thrombosis and phagocytosis. Gas6 and protein S have been identified as ligands for these receptors. Gas6 binding induces tyrosine phosphorylation and downstream signaling pathways that can lead to cell proliferation, migration, or the prevention of apoptosis. Tyro3 and Axl play important regulatory roles in a variety of tissues, including the central nervous, reproductive, immune, and vascular systems. Tyro3 is widely expressed during embryonic development and preferentially expressed during neurogenesis in the central nervous system.

Chemical Properties

Molecular Weight

90-120 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.