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ISOTHIAZOLINE 1,1-DIOXIDE

Name: ISOTHIAZOLINE 1,1-DIOXIDE
Brand: TargetMol
SKU: T8615
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T8615Cas No. 5908-62-3

Alias isothiazolidine 1,1-dioxide

ISOTHIAZOLINE 1,1-DIOXIDE (isothiazolidine 1,1-dioxide) is a reactant used in the synthesis of orally bioavailable hebatits B caspid inhibitors, and in the preparation of cryptochrome imhibitors as antidiabetic agents.

ISOTHIAZOLINE 1,1-DIOXIDE

🥰Excellent

Purity: 97.90%

Catalog No. T8615Alias isothiazolidine 1,1-dioxideCas No. 5908-62-3

Pack Size	Price	Availability	Quantity
200 mg	$29	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:97.90%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	ISOTHIAZOLINE 1,1-DIOXIDE (isothiazolidine 1,1-dioxide) is a reactant used in the synthesis of orally bioavailable hebatits B caspid inhibitors, and in the preparation of cryptochrome imhibitors as antidiabetic agents.
Synonyms	isothiazolidine 1,1-dioxide

Chemical Properties

Molecular Weight	121.16
Formula	C₃H₇NO₂S
Cas No.	5908-62-3
Smiles	O=S1(=O)CCC=N1
Relative Density.	1.326 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 27.5 mg/mL (226.97 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	8.2535 mL	41.2677 mL	82.5355 mL	412.6775 mL
5 mM	1.6507 mL	8.2535 mL	16.5071 mL	82.5355 mL
10 mM	0.8254 mL	4.1268 mL	8.2535 mL	41.2677 mL
20 mM	0.4127 mL	2.0634 mL	4.1268 mL	20.6339 mL
50 mM	0.1651 mL	0.8254 mL	1.6507 mL	8.2535 mL
100 mM	0.0825 mL	0.4127 mL	0.8254 mL	4.1268 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc