store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SL 0101-1 (SL0101) is a selective, efficient, reversible and ATP-competitive inhibitor of p90 ribosomal S6 kinase (RSK) that can permeate cell membranes, with an IC50 value of 89 nM for RSK.SL 0101-1 (SL0101) is also a potent RSK1/2 inhibitor with a Ki value of 1 μM. SL 0101-1 (SL0101) is also a potent RSK1/2 inhibitor with a Ki value of 1 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 143.00 | |
1 mg | 35 days | $ 250.00 | |
5 mg | 35 days | $ 988.00 | |
10 mg | 35 days | $ 1,360.00 |
Description | SL 0101-1 (SL0101) is a selective, efficient, reversible and ATP-competitive inhibitor of p90 ribosomal S6 kinase (RSK) that can permeate cell membranes, with an IC50 value of 89 nM for RSK.SL 0101-1 (SL0101) is also a potent RSK1/2 inhibitor with a Ki value of 1 μM. SL 0101-1 (SL0101) is also a potent RSK1/2 inhibitor with a Ki value of 1 μM. |
Targets&IC50 | RSK:89 nM |
In vitro | SL 0101-1 (SL0101) induces proliferation inhibition in the human breast cancer cell line MCF-7 and causes a cell cycle block in the G1 phase[1]. |
Synonyms | SL0101 |
Molecular Weight | 516.45 |
Formula | C25H24O12 |
CAS No. | 77307-50-7 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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SL 0101-1 77307-50-7 MAPK PI3K/Akt/mTOR signaling S6 Kinase SL 0101 SL-0101 SL0101 inhibitor inhibit