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PF-06795071

Catalog No. T16496 CAS 2075629-81-9

PF-06795071 is an effective and selective covalent inhibitor of MAGL (IC50: 3 nM).

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PF-06795071, CAS 2075629-81-9

Pack Size	Availability	Price/USD
5 mg	10-14 weeks	$ 1,570.00 $ 1,256.00
50 mg	10-14 weeks	$ 3,180.00 $ 2,544.00
100 mg	10-14 weeks	$ 4,300.00 $ 3,440.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	PF-06795071 is an effective and selective covalent inhibitor of MAGL (IC50: 3 nM).
Targets&IC50	MAGL:3 nM
In vitro	PF-06795071 displays excellent selectivity against FAAH (IC50: 3.1 μM)[1].

Molecular Weight	399.34
Formula	C18H17F4N3O3
CAS No.	2075629-81-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. McAllister LA, et al. Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation. J Med Chem. 2018 Apr 12;61(7):3008-3026.

Related Products

Related compounds with same targets

MAGL-IN-1 Atglistatin ABX-1431 JZL195 XEN445 AA38-3 Beta-Sitosterol URB602

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

PF-06795071 2075629-81-9 Metabolism Lipase PF 06795071 PF06795071 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.