Powder: -20°C for 3 years
In solvent: -80°C for 2 years
KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 nM, 4.274 μM for LMP2 and LMP7, respectively).
Description | KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 nM, 4.274 μM for LMP2 and LMP7, respectively). |
Targets&IC50 | LMP2:51 nM, LMP7:4.274 μM |
In vivo | Evaluating the inhibition of LMP2, and antitargets LMP7 and β5, in mouse tissues reveals that KZR-504 is both selective and potent in vivo. In all tissues tested except the brain, it has >50% target inhibition achieved at >1 mg/kg [1]. |
Molecular Weight | 413.42 |
Formula | C21H23N3O6 |
CAS No. | 1629052-78-3 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
KZR-504 1629052-78-3 Proteases/Proteasome Ubiquitination Proteasome KZR 504 KZR504 Inhibitor inhibitor inhibit