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Fosravuconazole

Catalog No. T15342 CAS 351227-64-0

Synonyms: BMS-379224, E-1224

Fosravuconazole is a ravuconazole prodrug. It has <a href="/target/Antifungal" style="display: inline; color: #c13a36">Antifungal</a> activity.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Fosravuconazole, CAS 351227-64-0

Pack Size	Availability	Price/USD
5 mg	8-10 weeks	$ 970.00
50 mg	8-10 weeks	$ 1,980.00
100 mg	8-10 weeks	$ 2,500.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Fosravuconazole is a ravuconazole prodrug. It has antifungal activity.
In vivo	Fosravuconazole displays comparable efficacy at inhibiting the C. Albicans infection model in mice as orally administered ravuconazole. Upon iv administration to rats, Fosravuconazole rapidly converses with ravuconazole.

Synonyms	BMS-379224, E-1224
Molecular Weight	547.47
Formula	C23H20F2N5O5PS
CAS No.	351227-64-0

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Ueda Y, et al. Phosphonooxymethyl prodrugs of the broad spectrum antifungal azole, ravuconazole: synthesis and biological properties. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3669-72.

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Fosravuconazole 351227-64-0 Microbiology/Virology Antifungal BMS-379224 E-1224 Inhibitor inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.