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BMY-25271

Catalog No. T10575   CAS 78441-82-4

BMY-25271 is an antagonist of histamine H2 receptor.

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BMY-25271 Chemical Structure
BMY-25271, CAS 78441-82-4
Pack Size Availability Price/USD Quantity
25 mg 6-8 weeks $ 1,520.00
50 mg 6-8 weeks $ 1,980.00
100 mg 6-8 weeks $ 2,500.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description BMY-25271 is an antagonist of histamine H2 receptor.
In vivo The dose-response curves are parallel and oral ED50 values derived from probit analysis are 0.093, 0.97, and 6.9 mg/kg for BMY-25271, ranitidine, and cimetidine, respectively. BMY-25271 is about 10 and 74 times more potent than ranitidine and cimetidine, respectively.
Molecular Weight 329.44
Formula C12H19N5O2S2
CAS No. 78441-82-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Cavanagh RL, et al. Prevention of aspirin-induced gastric mucosal injury by histamine H2 receptor antagonists: a crossover endoscopic and intragastric pH study in the dog. J Pharmacol Exp Ther. 1987 Dec;243(3):1179-84.

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Keywords

BMY-25271 78441-82-4 GPCR/G Protein Immunology/Inflammation Neuroscience Histamine Receptor BMY 25271 BMY25271 inhibitor inhibit

 

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