Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BMS-986118 is a full agonist of GPR40, is a G-protein-coupled receptor expressed primarily in pancreatic islets and intestinal L-cells that has been a target of significant recent therapeutic interest for type II diabetes. Activation of GPR40 by partial agonists elicits insulin secretion only in the presence of elevated blood glucose levels, minimizing the risk of hypoglycemia.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 2,720.00 | |
50 mg | 10-14 weeks | $ 3,580.00 | |
100 mg | 10-14 weeks | $ 4,900.00 |
Description | BMS-986118 is a full agonist of GPR40, is a G-protein-coupled receptor expressed primarily in pancreatic islets and intestinal L-cells that has been a target of significant recent therapeutic interest for type II diabetes. Activation of GPR40 by partial agonists elicits insulin secretion only in the presence of elevated blood glucose levels, minimizing the risk of hypoglycemia. |
Targets&IC50 | FFA1/GPR40:0.07 µM (IC50) |
Synonyms | BMS 986118 |
Molecular Weight | 540.96 |
Formula | C25H28ClF3N4O4 |
CAS No. | 1610562-74-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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BMS-986118 1610562-74-7 BMS986118 BMS 986118 inhibitor inhibit