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Acorafloxacin HCl

Catalog No. T23622 CAS 1001162-01-1

Synonyms: JNJ-32729463, JNJ-Q2 hydrochloride, Acorafloxacin hydrochloride, JNJ 32729463, JNJ-Q2 HCl

Acorafloxacin is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and skin structure infections and community-acquired pneumonia.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Acorafloxacin HCl, CAS 1001162-01-1

Pack Size	Availability	Price/USD
25 mg	8-10 weeks	$ 2,120.00
50 mg	8-10 weeks	$ 2,780.00
100 mg	8-10 weeks	$ 3,700.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Acorafloxacin is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and skin structure infections and community-acquired pneumonia.

Synonyms	JNJ-32729463, JNJ-Q2 hydrochloride, Acorafloxacin hydrochloride, JNJ 32729463, JNJ-Q2 HCl
Molecular Weight	455.88
Formula	C21H24ClF2N3O4
CAS No.	1001162-01-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Mattes TA, Escalante-Semerena JC. Facile isolation of α-ribazole from vitamin B(12) hydrolysates using boronate affinity chromatography. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 May 16;1090:52-55. doi: 10.1016/j.jchromb.2018.05.022. [Epub ahead of print] PubMed PMID: 29783174. 2. Rudnicki K, Poltorak L, Skrzypek S, Sudholter EJR. Fused silica micro-capillaries used for a simple miniaturization of the electrified liquid - liquid interface. Anal Chem. 2018 May 21. doi: 10.1021/acs.analchem.8b01351. [Epub ahead of print] PubMed PMID: 29781599. 3. Cao XY, Kong FZ, Zhang Q, Liu WW, Liu XP, Li GQ, Zhong R, Fan LY, Xiao H, Cao CX. iPhone-imaged and cell-powered electrophoresis titration chip for the alkaline phosphatase assay in serum by the moving reaction boundary. Lab Chip. 2018 May 21. doi: 10.1039/c8lc00163d. [Epub ahead of print] PubMed PMID: 29780999. 4. Isaacson SH, Fahn S, Pahwa R, Tanner CM, Espay AJ, Trenkwalder C, Adler CH, Patni R, Johnson R. Parkinson's Patients with Dyskinesia Switched from Immediate Release Amantadine to Open-label ADS-5102. Mov Disord Clin Pract. 2018 Mar-Apr;5(2):183-190. doi: 10.1002/mdc3.12595. Epub 2018 Feb 23. PubMed PMID: 29780852; PubMed Central PMCID: PMC5947645.

Dose Conversion

You can also refer to dose conversion for different animals. More

In vivo Formulation Calculator (Clear solution)

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

Calculator

Molarity Calculator

Dilution Calculator

Reconstitution Calculation

Molecular Weight Calculator

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Molarity Calculator allows you to calculate the

Mass of a compound required to prepare a solution of known volume and concentration
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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
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The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

Molecular Weight g/mol

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Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:
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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Acorafloxacin HCl 1001162-01-1 Acorafloxacin Hydrochloride JNJ-32729463 JNJ-Q2 hydrochloride Acorafloxacin hydrochloride JNJ 32729463 JNJ-Q2 Hydrochloride JNJ-Q2 HCl JNJ32729463 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.