RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His)

Catalog No. TMPK-00591 Copy Product Info

Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 28.97 kDa and the accession number is AAC40113.1.

RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His)

Catalog No. TMPK-00591

Copy Product Info

RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His)

Pack Size	Price	USA Stock	Global Stock
5 μg	$58	7-10 days	7-10 days
10 μg	$92	7-10 days	7-10 days
20 μg	$148	7-10 days	7-10 days
50 μg	$289	7-10 days	7-10 days
100 μg	$487	7-10 days	7-10 days
200 μg	$883	7-10 days	7-10 days
500 μg	$1,950	7-10 days	7-10 days

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In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Biological Activity	Immobilized Mouse RANKL, His Tag at 1 μg/mL (100 μL/well) on the plate. Dose response curve for Mouse TNFRSF11A, hFc Tag with the EC50 of 4.0 ng/mL determined by ELISA (QC Test).
Description	Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 28.97 kDa and the accession number is AAC40113.1.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-His
Accession Number	AAC40113.1
Synonyms	TRANCE,TNFSF11,sOdf,RANKL,OPTB2,OPGL,ODF,CD254
Construction	Tyr70-Asp316
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	28.97 kDa (predicted). Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Proteins are shipped with blue ice.
Research Background	Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone.