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Anti-DDR1/CD167a Antibody

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Catalog No. T9901A-1439

Anti-DDR1/CD167a Antibody is a neutralizing monoclonal antibody targeting the receptor tyrosine kinase DDR1, acting by blocking its interaction with extracellular matrix collagen. The compound is an essential tool for investigating how cell-matrix interactions regulate stem cell fate and tissue morphogenesis, aiming to reveal the molecular logic of multi-lineage differentiation and organ regeneration by intervening in the DDR1 signaling axis.

Anti-DDR1/CD167a Antibody

Anti-DDR1/CD167a Antibody

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Catalog No. T9901A-1439
Anti-DDR1/CD167a Antibody is a neutralizing monoclonal antibody targeting the receptor tyrosine kinase DDR1, acting by blocking its interaction with extracellular matrix collagen. The compound is an essential tool for investigating how cell-matrix interactions regulate stem cell fate and tissue morphogenesis, aiming to reveal the molecular logic of multi-lineage differentiation and organ regeneration by intervening in the DDR1 signaling axis.
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Product Introduction

Bioactivity
Description
Anti-DDR1/CD167a Antibody is a neutralizing monoclonal antibody targeting the receptor tyrosine kinase DDR1, acting by blocking its interaction with extracellular matrix collagen. The compound is an essential tool for investigating how cell-matrix interactions regulate stem cell fate and tissue morphogenesis, aiming to reveal the molecular logic of multi-lineage differentiation and organ regeneration by intervening in the DDR1 signaling axis.
In vitro
In 3D organoid cultures of primary mammary epithelial cells, Anti-DDR1/CD167a Antibody significantly reduced the frequency of colony-forming units and disrupted differentiation balance [1].
In vivo
In mouse models of mammary tissue regeneration, systemic administration of Anti-DDR1/CD167a Antibody inhibited ductal outgrowth and blocked terminal differentiation [1].
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetDDR1/CD167a
Chemical Properties
Antibody Information
IsotypeIgG1
Storage & Solubility Information
Storagestore at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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