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Anti-DDR1/CD167a Antibody is a neutralizing monoclonal antibody targeting the receptor tyrosine kinase DDR1, acting by blocking its interaction with extracellular matrix collagen. The compound is an essential tool for investigating how cell-matrix interactions regulate stem cell fate and tissue morphogenesis, aiming to reveal the molecular logic of multi-lineage differentiation and organ regeneration by intervening in the DDR1 signaling axis.

| Description | Anti-DDR1/CD167a Antibody is a neutralizing monoclonal antibody targeting the receptor tyrosine kinase DDR1, acting by blocking its interaction with extracellular matrix collagen. The compound is an essential tool for investigating how cell-matrix interactions regulate stem cell fate and tissue morphogenesis, aiming to reveal the molecular logic of multi-lineage differentiation and organ regeneration by intervening in the DDR1 signaling axis. |
| In vitro | In 3D organoid cultures of primary mammary epithelial cells, Anti-DDR1/CD167a Antibody significantly reduced the frequency of colony-forming units and disrupted differentiation balance [1]. |
| In vivo | In mouse models of mammary tissue regeneration, systemic administration of Anti-DDR1/CD167a Antibody inhibited ductal outgrowth and blocked terminal differentiation [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | DDR1/CD167a |
| Isotype | IgG1 |
| Storage | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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