keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
[Asn23] β-Amyloid (1-40), Iowa mutation, is a biologically active peptide associated with autosomal dominant Alzheimer's Disease in multiple families. This specific mutation involves the substitution of Asp 23 with Asn, leading to severe cerebral amyloid beta-protein angiopathy (CAA). Individuals with this mutation exhibit a missense alteration in the APP gene at position 694, which results in the mutated β-amyloid peptide aggregating more quickly and forming toxic fibrils.
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Description | [Asn23] β-Amyloid (1-40), Iowa mutation, is a biologically active peptide associated with autosomal dominant Alzheimer's Disease in multiple families. This specific mutation involves the substitution of Asp 23 with Asn, leading to severe cerebral amyloid beta-protein angiopathy (CAA). Individuals with this mutation exhibit a missense alteration in the APP gene at position 694, which results in the mutated β-amyloid peptide aggregating more quickly and forming toxic fibrils. |
Molecular Weight | N/A |
CAS No. | 374796-72-2 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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[Asn23] β-Amyloid (1-40), Iowa mutation 374796-72-2 inhibitor inhibit