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Sodium Houttuyfonate

Catalog No. TN5284 CAS 83766-73-8

Synonyms: Houttuynin sodium bisulfite

Sodium Houttuyfonate (Houttuynin sodium bisulfite), the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.

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Sodium Houttuyfonate, CAS 83766-73-8

Pack Size	Availability	Price/USD	Quantity
20 mg	In stock	$ 45.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Sodium Houttuyfonate (Houttuynin sodium bisulfite), the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.
In vitro	Treatment with sodium houttuyfonate results in an increase in the expression of c-Fos protein in macrophages, while the phosphorylation level of extracellular signal-related kinase 1/2 (ERK1/2) is not affected by the treatment[1].
In vivo	Sodium houttuyfonate has been shown to protect against cationized bovine serum albumin (C-BSA)-induced glomerulonephritis in BALB/C mice through the suppression of the urine protein, morphological character and monocyte chemotactic protein 1 (MCP-1)[1].

Synonyms	Houttuynin sodium bisulfite
Molecular Weight	302.36
Formula	C12H23NaO5S
CAS No.	83766-73-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 320 mg/mL (66.15 mM), Sonification is recommended

H2O: 3.33 mg/mL (11.02 mM), Sonification is recommended

References and Literature

1. Chen J, Wang W, Shi C, Fang J. A comparative study of sodium houttuyfonate and 2-undecanone for their in vitro and in vivo anti-inflammatory activities and stabilities. Int J Mol Sci. 2014;15(12):22978-22994. Published 2014 Dec 11. doi:10.3390/ijms151222978

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Anti-Cancer Drug Library Anti-Cancer Clinical Compound Library Anti-Inflammatory Traditional Chinese Medicine Compound Library NF-κB Signaling Compound Library Anti-Prostate Cancer Compound Library RO5 Drug-like Natural Product Library Anti-Breast Cancer Compound Library Natural Product Library for HTS Bioactive Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Keywords

Sodium Houttuyfonate 83766-73-8 Microbiology/Virology NF-Κb NF-κB Antibacterial Antifungal Houttuynin sodium Bisulfite Houttuynin sodium bisulfite inhibitor inhibit

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