Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 112.00 | |
5 mg | In stock | $ 239.00 | |
10 mg | In stock | $ 397.00 | |
25 mg | In stock | $ 663.00 | |
50 mg | In stock | $ 945.00 | |
100 mg | In stock | $ 1,280.00 |
Description | SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes. |
Targets&IC50 | HDAC6:12 nM, HDAC8:1.23 μM, HDAC1:1.39 μM, HDAC11:5.12 μM, HDAC5:6.91 μM, HDAC7:8.34 μM |
In vivo | In C57BL/6 mice injected immunogenic murine SM1 melanoma cells, SS-208 (25 mg/kg; i.p.) causes a significant reduction of the tumor growth[1]. |
Molecular Weight | 344.15 |
Formula | C13H11Cl2N3O4 |
CAS No. | 2245942-72-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (290.6 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SS-208 2245942-72-5 Chromatin/Epigenetic DNA Damage/DNA Repair HDAC SS 208 SS208 inhibitor inhibit