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Rufloxacin

Catalog No. T21035 CAS 101363-10-4

Synonyms: MF 934

Rufloxacin is a drug that belongs to the class of fluoroquinolones, which act mainly as specific inhibitors of bacterial Topoisomerase II. These drugs involve in various diseases including cutaneous reactions, aging, etc.

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Rufloxacin, CAS 101363-10-4

Pack Size	Availability	Price/USD
25 mg	8-10 weeks	$ 1,820.00
50 mg	8-10 weeks	$ 2,380.00
100 mg	8-10 weeks	$ 3,100.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	MF 934
Molecular Weight	363.41
Formula	C17H18FN3O3S
CAS No.	101363-10-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Soluble

References and Literature

1. Gismondo MR, Drago L, Lombardi A, Fassina C, Cesana M. Impact of rufloxacin and ciprofloxacin on the intestinal microflora in a germ-free mice model. Chemotherapy. 1995 Jul-Aug;41(4):281-8. PubMed PMID: 7555209. 2. Lazzaroni M, Imbimbo BP, Bargiggia S, Sangaletti O, Dal Bo L, Broccali G, Bianchi Porro G. Effects of magnesium-aluminum hydroxide antacid on absorption of rufloxacin. Antimicrob Agents Chemother. 1993 Oct;37(10):2212-6. PubMed PMID: 8257146; PubMed Central PMCID: PMC192252. 3. Gu LY, Lin WW, Lu H, Chen XY, Ge ZZ, Li XB. Quadruple therapy with medications containing either rufloxacin or furazolidone as a rescue regimen in the treatment of Helicobacter pylori-infected dyspepsia patients: a randomized pilot study. Helicobacter. 2011 Aug;16(4):284-8. doi: 10.1111/j.1523-5378.2011.00848.x. PubMed PMID: 21762267. 4. Catalfo A, Scifo C, Stella S, Belvedere A, Renis M, De Guidi G. Rufloxacin induced photosensitization in bio-models of increasing complexity. Photochem Photobiol Sci. 2005 Mar;4(3):304-14. Epub 2005 Feb 2. PubMed PMID: 15739000.

Dose Conversion

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Molarity Calculator

Dilution Calculator

Reconstitution Calculation

Molecular Weight Calculator

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Mass of a compound required to prepare a solution of known volume and concentration
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Concentration of a solution resulting from a known mass of compound in a specific volume

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
Press calculate
The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Rufloxacin 101363-10-4 MF-934 MF934 MF 934 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.