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Pecilocin

Catalog No. T25926 CAS 19504-77-9

Synonyms: NSC-291839, NSC291839, Supral, Pecilocinum, NSC 291839

Pecilocin is a fungicidal antibiotic generated by Paecilomyces varioti Bainier var. antibioticus.

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Pecilocin, CAS 19504-77-9

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Pecilocin is a fungicidal antibiotic generated by Paecilomyces varioti Bainier var. antibioticus.

Synonyms	NSC-291839, NSC291839, Supral, Pecilocinum, NSC 291839
Molecular Weight	291.391
Formula	C17H25NO3
CAS No.	19504-77-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Harris C, Philpot CM. A comparative trial of chlorphenesin and pecilocin in a prison community. Br J Clin Pract. 1969 Nov;23(11):449-51. PubMed PMID: 4900295. 2. Norgaard O. [Pecilocin allergy]. Hautarzt. 1977 Jan;28(1):35-6. German. PubMed PMID: 138665. 3. Mizushina Y, Suzuki-Fukudome H, Takeuchi T, Takemoto K, Kuriyama I, Yoshida H, Kamisuki S, Sugawara F. Formosusin A, a novel specific inhibitor of mammalian DNA polymerase β from the fungus Paecilomyces formosus. Bioorg Med Chem. 2014 Feb 1;22(3):1070-6. doi: 10.1016/j.bmc.2013.12.038. Epub 2013 Dec 25. PubMed PMID: 24411199. 4. van Miert AS, van Soeren JH, Hagens FM. [Antimycotic antibiotics (author's transl)]. Tijdschr Diergeneeskd. 1976 Aug 15;101(16):900-4. Dutch. PubMed PMID: 1085044.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Pecilocin 19504-77-9 NSC-291839 NSC291839 Supral Pecilocinum NSC 291839 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.