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PF-03654746 Tosylate

Catalog No. T12416   CAS 1039399-17-1

PF-03654746 Tosylate is selective antagonist of histamine H3 receptor with high brain penetration.

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PF-03654746 Tosylate Chemical Structure
PF-03654746 Tosylate, CAS 1039399-17-1
Pack Size Availability Price/USD Quantity
5 mg 6-8 weeks $ 297.00
50 mg 6-8 weeks $ 1,180.00
100 mg 6-8 weeks $ 1,790.00
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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.
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Biological Description
Chemical Properties
Storage & Solubility Information
Description PF-03654746 Tosylate is selective antagonist of histamine H3 receptor with high brain penetration.
Molecular Weight 494.6
Formula C25H32F2N2O4S
CAS No. 1039399-17-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

TargetMolReferences and Literature

1. Stokes JR, et al. The effects of an H3 receptor antagonist (PF-03654746) with fexofenadine on reducing allergic rhinitis symptoms. J Allergy Clin Immunol. 2012 Feb;129(2):409-12, 412.e1-2. 2. Brioni JD, et al. Discovery of histamine H3 antagonists for the treatment of cognitive disorders and Alzheimer's disease. J Pharmacol Exp Ther. 2011 Jan;336(1):38-46.

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PF-03654746 Cyclizine dihydrochloride Corchoionoside C Cetirizine D8 H4R antagonist 3 Dothiepin H4R antagonist 2 4-Methylhistamine

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Keywords

PF-03654746 Tosylate 1039399-17-1 GPCR/G Protein Immunology/Inflammation Neuroscience Histamine Receptor PF 03654746 Tosylate PF03654746 Tosylate inhibitor inhibit

 

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