Powder: -20°C for 3 years | In solvent: -80°C for 1 year
OBAA is a potent inhibitor of phospholipase A2 (PLA2) with an IC 50 of 70 nM. OBAA blocks Melittin-induced Ca 2+ influx in Trypanosoma brucei with an IC 50 of 0.4 μM [1] [2] [3].
Description | OBAA is a potent inhibitor of phospholipase A2 (PLA2) with an IC 50 of 70 nM. OBAA blocks Melittin-induced Ca 2+ influx in Trypanosoma brucei with an IC 50 of 0.4 μM [1] [2] [3]. |
In vitro | OBAA (5.7 μM) induces apoptotic cell death of human umbilical vein endothelial cells (HUVEC). Nearly all of the cells had disintegrated into apoptotic bodies after 16h of treatment [1]. |
In vivo | The immunologically induced bronchospasm in guinea pigs is markedly and dose-dependently inhibited by OBAA (2.5-7 mg/kg i.v.) [3]. |
Molecular Weight | 428.65 |
Formula | C28H44O3 |
CAS No. | 221632-26-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: <1 mg/mL
You can also refer to dose conversion for different animals. More
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OBAA 221632-26-4 Others inhibitor inhibit