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2,4-Difluorobenzaldehyde

Name: 2,4-Difluorobenzaldehyde
Brand: TargetMol
SKU: T9354
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9354Cas No. 1550-35-2

Alias 2,4-Difluoro-benzaldehyde

2,4-Difluorobenzaldehyde can act on the light chain of botulinum neurotoxin type A (BoNT/A), inhibiting the cleavage of BoNT A light chain, ic50=4.9μM.

2,4-Difluorobenzaldehyde

🥰Excellent

Purity: 99.42%

Catalog No. T9354Alias 2,4-Difluoro-benzaldehydeCas No. 1550-35-2

2,4-Difluorobenzaldehyde can act on the light chain of botulinum neurotoxin type A (BoNT/A), inhibiting the cleavage of BoNT A light chain, ic50=4.9μM.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
5 g	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.42%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	2,4-Difluorobenzaldehyde can act on the light chain of botulinum neurotoxin type A (BoNT/A), inhibiting the cleavage of BoNT A light chain, ic50=4.9μM.
Synonyms	2,4-Difluoro-benzaldehyde

Chemical Properties

Molecular Weight	142.1
Formula	C₇H₄F₂O
Cas No.	1550-35-2
Smiles	FC1=CC(F)=C(C=O)C=C1
Relative Density.	1.299g/mLat 25°C(lit.)
Color	Transparent
Appearance	Liquid

Storage & Solubility Information

Storage

store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (422.24 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (14.07 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	7.0373 mL	35.1865 mL	70.3730 mL	351.8649 mL
5 mM	1.4075 mL	7.0373 mL	14.0746 mL	70.3730 mL
10 mM	0.7037 mL	3.5186 mL	7.0373 mL	35.1865 mL
20 mM	0.3519 mL	1.7593 mL	3.5186 mL	17.5932 mL
50 mM	0.1407 mL	0.7037 mL	1.4075 mL	7.0373 mL
100 mM	0.0704 mL	0.3519 mL	0.7037 mL	3.5186 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc