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Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
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Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
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DNA Damage & Repair Compound Library

Catalog No. L3900
  Library Compound List   Excel SDF

A significant barrier to effective cancer therapy is the development of resistance to the drugs utilized, therefore, identifying new biological targets and designing new drugs becomes one of the most important strategies. Among the various potential targets, DNA damage and repair system in cancer cells is one of the most pivotal targets. The use of unspecific antibiotics to treat bacterial infections has caused a great deal of multiple resistant strains making less effective the current therapies with antibiotics. Developing inhibitors of DNA repair and related pathways in pathogens will have utility in the treatment of infections.

The TargetMol’s DNA Damage & Repair Compound Library, a unique collection of 937 DNA Damage & Repair related compounds, can be used for research in DNA damage and repair, and high throughput screening (HTS) and high content screening (HCS).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Compound Libraries | TargetMol
Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
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Product Description

  • A unique collection of 937 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Targets include HDAC, DNA/RNA synthesis, Topoisomerase, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files
Request Library Compound List (L3900)

Publications Cited TargetMol Libraries

1. International Journal of Cancer. 2022. 2. Cancer Letters. 2020. 3. International Journal of Cancer. 2022 Aug 15;151(4):590-606. 4. Cell Stem Cell. 2022 Apr 29(4) 545–558. 5. Science Bulletin. 2022. 6. Science Translational Medicine. 2022, 14(656): eabn3231. 7. Science Advances. 2023, 9(9): eade3760. 8. Nature. 2020, 582: 289-293. 9. Nature Biotechnology. 2021, 39(11): 1444-1452.
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Library Composition

DNA/RNA Synthesis (237)
Apoptosis (144)
PPAR (125)
HDAC (117)
Autophagy (110)
Topoisomerase (102)
Antibacterial (80)
PARP (77)
Antibiotic (68)
Nucleoside Antimetabolite/Analog (63)
Sirtuin (57)
Endogenous Metabolite (54)
DNA-PK (38)
DUB (35)
PI3K (31)
DNA Alkylator/Crosslinker (25)
ATM/ATR (24)
Influenza Virus (20)
HIV Protease (19)
mTOR (19)
Parasite (19)
DNA Alkylation (18)
HSV (16)
DNA (16)
COX (15)
NF-κB (15)
DNA gyrase (15)
DHFR (15)
Dehydrogenase (15)
Reactive Oxygen Species (13)
Telomerase (13)
Caspase (12)
Mitophagy (11)
Antifolate (11)
SARS-CoV (10)
Wnt/beta-catenin (10)
Potassium Channel (9)
Virus Protease (9)
Ferroptosis (9)
BCL (9)
Antifungal (9)
P450 (8)
HCV Protease (8)
p38 MAPK (8)
p53 (8)
PDE (8)
HBV (7)
AMPK (7)
Antifection (6)
CRISPR/Cas9 (6)
IL Receptor (6)
Epigenetic Reader Domain (5)
Reverse Transcriptase (5)
TNF (5)
GABA Receptor (5)
Nrf2 (5)
BMI-1 (5)
Akt (5)
Tyrosinase (5)
MTH1 (5)
PKC (5)
Sodium Channel (5)
AChR (5)
TGF-beta/Smad (4)
Adenosine Receptor (4)
PKA (4)
DNA Methyltransferase (4)
Bcr-Abl (4)
CDK (4)
Prostaglandin Receptor (4)
Drug Metabolite (4)
Lipoxygenase (4)
FLT (3)
ATPase (3)
STAT (3)
NMDAR (3)
Histone Demethylase (3)
Carbonic Anhydrase (3)
Mitochondrial Metabolism (3)
transporter (3)
MMP (3)
Calcium Channel (3)
TRP/TRPV Channel (3)
GPR (3)
EGFR (3)
Interleukin (3)
Retinoid Receptor (2)
ribosome (2)
5-HT Receptor (2)
Proteasome (2)
Arginase (2)
NADPH (2)
Antiviral (2)
NO Synthase (2)
Anti-infection (2)
RAAS (2)
MEK (2)
PAK (2)
Phosphatase (2)
Phospholipase (2)
Microtubule Associated (2)
PI4K (2)
Mdm2 (2)
Adenosine deaminase (2)
c-Met/HGFR (2)
cGAS (2)
VEGFR (2)
Cysteine Protease (2)
Tyrosine Kinases (2)
Casein Kinase (2)
Carboxypeptidase (2)
Cannabinoid Receptor (2)
ERK (2)
Transferase (2)
Free radical scavengers (2)
Gamma-secretase (2)
HIF/HIF Prolyl-Hydroxylase (2)
Thrombin (2)
JAK (2)
Adrenergic Receptor (2)
LDL (2)
Syk (2)
IAP (2)
ABC (2)
JNK (2)
IκB/IKK (2)
Raf (1)
ROS (1)
RSV (1)
PLK (1)
Serine/threonin kinase (1)
Aminopeptidase (1)
Ras (1)
Trk receptor (1)
Src (1)
Proton pump (1)
TLR (1)
ROCK (1)
TAM Receptor (1)
SGK (1)
Chk (1)
P-gp (1)
Glucokinase (1)
HSP (1)
Aurora Kinase (1)
Histone Acetyltransferase (1)
Histamine Receptor (1)
HER (1)
Hedgehog/Smoothened (1)
Glutathione Peroxidase (1)
FLAP (1)
IDO (1)
FAK (1)
Epoxide Hydrolase (1)
E1/E2/E3 Enzyme (1)
Dopamine Receptor (1)
CCR (1)
c-Fms (1)
c-RET (1)
c-Myc (1)
Hydrogenase (1)
IGF-1R (1)
PDGFR (1)
NOD (1)
Androgen Receptor (1)
PAFR (1)
PAD (1)
P2Y Receptor (1)
P2X Receptor (1)
OCT (1)
NOD-like Receptor (NLR) (1)
MRP (1)
iGluR (1)
c-Kit (1)
MLK (1)
Aromatase (1)
MAPK (1)
MAO (1)
LRRK2 (1)
Leukotriene Receptor (1)
KLF (1)
Monoamine Oxidase (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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