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TfR-T12 acetate
🥰Excellent
Catalog No. T40428L
Alias TfR-T12 acetate (344618-30-0 Free base)
TfR-T12 acetate is a peptide binding to the transferrin receptor (TfR) and is subsequently internalized into TfR-expressing cells.
TfR-T12 acetate
🥰Excellent
Purity: 97%
Catalog No. T40428LAlias TfR-T12 acetate (344618-30-0 Free base)
TfR-T12 acetate is a peptide binding to the transferrin receptor (TfR) and is subsequently internalized into TfR-expressing cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $87 | In Stock | |
| 5 mg | $176 | In Stock | |
| 10 mg | $293 | In Stock | |
| 25 mg | $527 | In Stock | |
| 50 mg | $762 | In Stock | |
| 100 mg | $1,070 | In Stock | |
| 500 mg | $2,130 | In Stock |
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Purity:97%
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Product Introduction
Bioactivity
Chemical Properties
| Description | TfR-T12 acetate is a peptide binding to the transferrin receptor (TfR) and is subsequently internalized into TfR-expressing cells. |
| In vitro | TfR-T12 acetate can be chemically conjugated with a pegylated lipid derivative, 3-(N-succinimidyloxyglutaryl)aminopropyl- polyethyleneglycol(2000)- carbamyl distearoyl phosphatidylethanolamine (NHS-PEG2000-DSPE), and used as a functional material to construct the multifunctional lipid vesicles[1]. |
| In vivo | In brain glioma-bearing mice, TfR-T12 acetate is transported across the BBB, killing brain glioma and glioma stem cells via the induction of necrosis, apoptosis and autophagy[2]. |
| Synonyms | TfR-T12 acetate (344618-30-0 Free base) |
| Molecular Weight | 1550.78 |
| Formula | C73H103N19O17S |
| Smiles | C[C@@H](O)[C@@H](C(N[C@@H](CC1=CN=CN1)C(N[C@@H](CCCNC(N)=N)C(N2CCC[C@H]2C(N3CCC[C@H]3C(N[C@H](C(N[C@@H](CC4=CNC5=CC=CC=C45)C(N[C@H](C(N6CCC[C@H]6C(N[C@H](C(N[C@H](C(N7[C@@H](CCC7)C(O)=O)=O)CC8=CNC9=CC=CC=C98)=O)C(C)C)=O)=O)CO)=O)=O)CCSC)=O)=O)=O)=O)=O)N.CC(O)=O |
| Color | White |
| Appearance | Solid |
| Sequence | Thr-His-Arg-Pro-Pro-Met-Trp-Ser-Pro-Val-Trp-Pro |
| Sequence Short | THRPPMWSPVWP |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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